Skip to main content

Clinically Extremely Vulnerable Adults

Last updated 1 July 2021

Adults with specified conditions that make them “clinically extremely vulnerable” are Priority Group 4 - let us know if you have not received your invitation for COVID-19 vaccination 


About the Clinically Extremely Vulnerable priority group

Adults who are "clinically extremely vulnerable" are in priority group 4 in the national priority groups for COVID-19 vaccination from the UK's independent Joint Committee on Vaccination and Immunisation.

In line with national guidance this category include:

  • Solid organ transplant recipients
  • People with specific cancers:
    • People with cancer who are undergoing active chemotherapy or radical radiotherapy for lung cancer
    • People with cancers of the blood or bone marrow such as leukaemia, lymphoma or myeloma who are at any stage of treatment
    • People having immunotherapy or other continuing antibody treatments for cancer
    • People having other targeted cancer treatments which can affect the immune system, such as protein kinase inhibitors or PARP inhibitors
    • People who have had bone marrow or stem cell transplants in the last 6 months, or who are still taking immunosuppression drugs
  • People with severe respiratory conditions including all cystic fibrosis, severe asthma and severe Chronic Obstructive Pulmonary Disease (COPD)
  • People with severe single organ disease (e.g. Liver, Cardio, Renal, Neurological).
  • People with rare diseases and inborn errors of metabolism that significantly increase the risk of infections (such as Severe Combined Immunodeficiency (SCID), homozygous sickle cell).
  • People on immunosuppression therapies sufficient to significantly increase risk of infection.
  • Adults with Down’s syndrome.
  • Pregnant women with significant heart disease, congenital or acquired*

*Please note that the current vaccines are not recommended for use by pregnant women or children under 16

More detailed information about how people are identified as “clinically extremely vulnerable” is available from the NHS Wales Informatics Service website.

People who are clinically extremely vulnerable will have received a letter earlier this year from Welsh Government with information about how to stay safe as all of Wales is in Coronavirus Alert Level 4.


First Dose Appointments

Please complete the form below if you have not received your first dose vaccination.


Second Dose Appointments

Information about second dose appointments is available from our second dose appointments page.


Further Information

More information about COVID-19 vaccination in Powys is available from our COVID-19 vaccination page.


You can find out how we process and store your data in the Privacy section of our website.

Connect: