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Clinically Extremely Vulnerable Adults

Last updated 11 November 2021

Let us know if you have a condition that makes you “clinically extremely vulnerable” to serious illness from COVID and have not received your first or second dose vaccination.


About the Clinically Extremely Vulnerable priority group

People aged 16+ who are "clinically extremely vulnerable" are in priority group 4 in the national priority groups for COVID-19 vaccination from the UK's independent Joint Committee on Vaccination and Immunisation.

In line with national guidance this category include:

  • Solid organ transplant recipients
  • People with specific cancers:
    • People with cancer who are undergoing active chemotherapy or radical radiotherapy for lung cancer
    • People with cancers of the blood or bone marrow such as leukaemia, lymphoma or myeloma who are at any stage of treatment
    • People having immunotherapy or other continuing antibody treatments for cancer
    • People having other targeted cancer treatments which can affect the immune system, such as protein kinase inhibitors or PARP inhibitors
    • People who have had bone marrow or stem cell transplants in the last 6 months, or who are still taking immunosuppression drugs
  • People with severe respiratory conditions including all cystic fibrosis, severe asthma and severe Chronic Obstructive Pulmonary Disease (COPD)
  • People with severe single organ disease (e.g. Liver, Cardio, Renal, Neurological).
  • People with rare diseases and inborn errors of metabolism that significantly increase the risk of infections (such as Severe Combined Immunodeficiency (SCID), homozygous sickle cell).
  • People on immunosuppression therapies sufficient to significantly increase risk of infection.
  • Adults with Down’s syndrome.
  • Pregnant women with significant heart disease, congenital or acquired

More detailed information about how people are identified as “clinically extremely vulnerable” is available from the NHS Wales Informatics Service website.

Guidance published in July 2021 has extended the vaccination programme to include children aged 12-15 with certain conditions that make them clinically extremely vulnerable.


First Dose Appointments for adults who are clinically extremely vulnerable

If you have not not received your invitation for COVID-19 vaccination you can attend a drop-in session.


Second Dose Appointments

Second dose appointments are under way. Find out more about second dose appointments from the Second Dose Appointments section of our website


Third Dose / Booster Programme

Welsh Government has adopted recommendations from the JCVI to offer a third dose to certain individuals with severe immunosuppression at the time of their first or second dose. We are working with specialist clinicians to identify those individuals who should be offered a third dose, and to recommend the timing of the third dose. Eligible individuals will normally by invited by their local health board. 


Booster Programme

Our booster programme is under way. Please visit our booster programme page for further information.


Further Information

More information about COVID-19 vaccination in Powys is available from our COVID-19 vaccination page.


You can find out how we process and store your data in the Privacy section of our website.

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