Skip to main content

Sodium Valproate Resources and Information

Resources

MHRA - Patient Guide: What you need to know about valproate

MHRA - Patient Card

All Wales Therapeutics and Toxicology Centre - Sodium valproate use by women and girls

As part of the collaborative effort of the Sodium Valproate Task Force established by Welsh Government, AWTTC (All Wales Therapeutics and Toxicology Centre) are pleased to announce that a hub of information focusing on ‘Sodium valproate use by women and girls’ is now available on their website, accessed using the link above.

Easy read leaflet for female medicine reviews

Decision Support Tools

Decision Support Tool: Bipolar Disorder - Is Valproate the Right Treatment for me?

Decision Support Tool: Is Valproate the Right Epilepsy Treatment for me?

Forms

MHRA - Annual Risk Acknowledgement Form for Female Patients

MHRA - Risk Acknowledgement Form for Male Patients Starting Valproate

 

Guidance

MHRA - Guide for Healthcare Professionals: Information on the risks of valproate use in all patients

MHRA - Valproate: Review of Safety Data and Expert Advice on Management of Risks

Pregnancy Testing and Contraception for Pregnancy Prevention During Treatment with Medicines of Teratogenic Potential

All Wales Therapeutics and Toxicology Centre - Sodium valproate use by women and girls

As part of the collaborative effort of the Sodium Valproate Task Force established by Welsh Government, AWTTC (All Wales Therapeutics and Toxicology Centre) are pleased to announce that a hub of information focusing on ‘Sodium valproate use by women and girls’ is now available on their website, accessed using the link above.

 

Alerts and Updates

MHRA drug safety update - Valproate: Updated safety and educational materials to support patient discussion on reproductive risks - June 2025

MHRA drug safety update - February 2025

MHRA Public Assessment Report - Sept 2024: Valproate - Paternal Exposure to Valproate and Risk of Neurodevelopmental Disorders (CEM CPhA 2024 041)

MHRA Drug Safety Update - January 2024

MHRA National Patient Safety Alert - November 2023 (NatPSA/2023/013/MHRA)

 

Paediatric Patients

RCPCH - Prescribing Valproate to Female Patients Under 18 Years of Age (Jan 2024)

RCPCH - Update for Valproate Prescribing in Paediatric Neurology (Jan 2024)

 

Community Pharmacy

Valproate Safe Supply - Community Pharmacy

Connect: